… , with a focus on immunoglobulin G (IgG) mAbs. Next, we will … appropriate derivatization
agents for LC-MS/MS analysis of N-… platform with an accompanying reduction of 50% in analysis …

… entry of the potent biosimilars hitting the market. In this work … for large therapeutic protein like
IgG 1 cysteine conjugated ADC (… drugs, LC–MS/MS-mediated glycoproteomic analysis was …

… of IgG-type antibodies, the affinity chromatography using … off-line steps and data analysis,
LC-MS/MS peptide mapping … and biosimilar antibodies, 123 high-resolution characterization of …

… D) LC-MS/MS N-glycan quantification of infliximab innovator … ion analysis. Images reproduced
with permission from Ref. [188]. D) Charge variants analysis of innovator and biosimilar …

… The previously developed online 4D-LC-MS/MS peptide … monitoring of a Trastuzumab
biosimilar produced by CHO cells, … its high resolving power and miniaturized format. Additionally, …

… Because of its simple instrumentation, miniaturized format … characterization of T-DM1 and
its biosimilar candidate using … the payload in LC-MS/MS analysis are very challenging mainly …

… Disregarding other products such as biosimilars or fusion proteins, in 2020 eleven antibody-…
A detailed characterization of such products is important since any small change in the …

… accompanied with the emerging biosimilar market for Fc-fusion … be simultaneously
characterized in a single LC–MS/MS analysis [45… miniaturized format, CE is also widely applied for …

… from environmental analysis to drug analysis and doping … comparison of originator mAbs
and biosimilars. Pisupati et al… Monolithic materials are well-suited for the design of miniaturized …

… B cell clone, belonging to the typical IgG subtype. They are highly … development process,
especially for biosimilar drug. This method … of characteristics between ELISA and LC-MS/MS. …